LabGenius

Senior Scientist ( Protein Production)

BiotechSenior
LabGenius
's Mission

LabGenius' mission is to build a closed-loop platform for the evolution of new biological components. Since the advent of life 3.8 billion years ago, the survival of all species has depended on rapid innovation at the genetic level. At LabGenius, they're harnessing evolution to develop a new generation of biological products in partnership with world-leading multinationals.

What you'll be doing

  • Maintaining and upgrading our eukaryotic expression facility; this will include establishing new expression cell lines from human, insect or yeast.
  • Leading target protein production, as well as optimising production methods for complex protein modalities.
  • Introducing new equipment and workflows to streamline the production of therapeutic candidate proteins.
  • Collaborating with our automation team to onboard new expression hosts into our automated high-throughput protein production platform.
  • Working closely with our high-throughput screening team to design and provide suitable protein constructs for different characterisation assays.
  • Training other team members in advanced expression and purification techniques.

Requirements

  • You’ll be passionate about protein production, with significant experience working with bacterial and eukaryotic expression systems.
  • You'll enjoy shaking things up for the better, with experience of advocating for, implementing, and validating new protein production technologies.
  • You’ll have worked on a variety of tricky targets, overcoming challenges to produce high-quality, high-yield proteins. This may include membrane proteins, mAbs, Fabs, or multi-valent biologics.
  • You’ll be a ÄKTA super-user with substantial expertise across a range of FPLC systems and workflows, e.g. developing automated workflows to increase purification throughput.
  • You'll have strong molecular biology skills, preferably with experience of cutting-edge cloning techniques such as Gibson assembly or Golden Gate.
  • You'll be able to demonstrable ability to up-skill more junior team members and explain scientific concepts to non-scientists, such as automation engineers.
  • You will have previous experience working with or developing high-throughput protein production systems.

Company Values

We're a diverse bunch, we're united by our values: commitment to each other, enthusiasm to teach and learn, and determination to build a successful business that benefits humanity.

Company Benefits

  • Flexible working arrangements: whether you’re a night owl or a morning lark, with core hours of 10am-4pm, you can choose a pattern that works for you.
  • Easy access to on-site gym and climbing wall (post-covid) to break a sweat or indulge your inner monkey.
  • Monthly 1-on-1 coaching from Sanctus: because we need to look after our minds as well as our bodies.
  • Self-service study budget via Sunlight plus books, courses, and events; we encourage personal development in any form. Basically, we heart learning.
  • Weekly team lunches from City Pantry: the perfect time to connect over kebabs, natter over nachos, or cackle over curry.
  • Access to the Cycle To Work scheme: to make your commute cheaper, healthier, and a whole lot greener!
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